Enicostemma axillare (EA) perennial herb found throughout in India and used in folk medicine to treat diabetes mellitus, rheumatisum, abdominal ulcers, hernia, swelling, itching and insect poisoning. The present study was undertaken to investigate effect of EA on haloperidol induced catalepsy in mice. The effect of deferent doses (100 and 200 mg/kg) of EA was studied on haloperidol (1 mg/kg, i.p.) induced catalepsy using bar test. The result indicated that haloperidol induced catalepsy was significantly potentiated by EA. Therefore, EA has cataleptic activity.
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